Mini organs: Small models, large impact

From basic research to personalized medicine with organoids When: 13th of October, 09:00-13:00 Where: LA21 + ground floor areas, Labsenteret, Øya, Trondheim Register here Research into the development and use of organoids has accelerated in recent years, and they are now widely applied in biomedical research. Organoids can provide researchers with personalized disease models when derived from a patient's own diseased tissue; this allows for the observation of individual disease progression and the testing of drugs directly on the patient's own cells. Additionally, organoids can be used for the safe testing of new drugs (without the use of animal models), studies on human development, and infection research. As with other areas of biomedical research, the development and use of organoids will proceed in conjunction with other disciplines; technology and infrastructure are therefore key factors. The aim of this event is to bring together professionals working in research and infrastructure at NTNU, SINTEF, and St. Olavs Hospital – to gain an overview of organoid research in Trondheim and to foster new connections and cross-disciplinary collaborations. Program 09:00-09:05 Welcome . Marius Widerøe and Trygve Brautaset (NTNU Health and Life Science) 09:05-09:45 Keynote : Creating complexity through supervised morphogenesis: stemcell-based embryo models. Stefan Krauss (OUS/UiO) 09:45-10:00 Break 10:00-11:00 Research from NTNU: Brain: From Childhood Dementia to Alzheimer's Disease: Insights from Human Brain Organoids. Magnar Bjørås and Kaja Scheffler Cancer: Prostate Organoids as a Window into Cancer Biology. May-Britt Tessem Title TBA. Åsmund Flobak Gastroenterology: Intestinal organoids from patients with Inflammatory Bowel Disease: From disease modelling to treatment response prediction. Torunn Bruland 11:00-13:00 Infrastructure at NTNU, SINTEF and St. Olavs. Stands, lunch and mingling. Confirmed infrastructures Genomics Core Facility Cellular and Molecular Imaging Core Facility Bioinformatics Core Facility MR Core Facility , Proteomics and Modomics Experimental Core Facility Comparative Medicine Core facility Forskningspoliklinikken, St. Olavs Hospital SINTEF Industri, Bioteknologi og nanomedisin Viral Vector Core facility Center for Advanced Microscopy NTNU Nanolab Transmission Electron Microscopy Gemini IKOM Electron Microscopy-lab The seminar is organised by NTNU Health and Life Science , one of five strategic research areas at NTNU . Image: Primary prostate cancer organoid. Prostomic group, PI May-Britt Tessem

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